INDEX       NEWS & MEDIA ROOM
Embed this Video
 
 

Share this on Twitter

 
Doctors @OSUWexMed develop a simple test to help spot early signs of Alzheimerís. Details here: bit.ly/1bAVDxY  
Link to this page:
 

Meet the Expert

Douglas Scharre, MD


click here to read more

Study: Self-Administered Test Helps Spot Early Alzheimer's

Finding symptoms early is crucial to treatment, self-administered paper test can help

(COLUMBUS, Ohio) January 2014 – Researchers have developed an self-administered test that can help doctors spot early symptoms of cognitive issues in their patients, like Alzheimer’s disease. Best of all, the test is cheap, self-administered, and can be taken virtually anywhere.

“What we found was that this self-administered test correlated very well with more detailed cognitive testing,” said Douglas Scharre, MD, who developed the test with his team at The Ohio State University Wexner Medical Center, “The difference is, this approach simply requires a pen, paper and about 10 minutes of a patient’s time,” he said.

While the test cannot definitely diagnose problems like Alzheimer's disease, it does allow doctors to screen for any cognitive deficits and to obtain baseline cognitive functioning that could be monitored over time. “We can give them the test periodically and the moment we notice any changes in their cognitive abilities, we can intervene much more rapidly,” said Scharre.

Doctors say early intervention is the key to good treatment outcomes. Unfortunately patients with Alzheimer’s disease, for example, often wait 3-4 years after their symptoms first appear to seek treatment. “Hopefully, this test will help change those situations,” said Scharre. To download the SAGE test click here. To learn more about the test click on the video box to the left. To read the press release, “click to read more” below.

 

 

 

 

 

 

 

 

SAGE TEST USEFUL TO SCREEN FOR MEMORY DISORDERS IN COMMUNITY SETTINGS, OHIO STATE STUDY SHOWS

COLUMBUS, Ohio – The Self-Administered Gerocognitive Examination (SAGE test), which takes less than 15 minutes to complete, is a reliable tool for evaluating cognitive abilities. Findings by researchers at The Ohio State University Wexner Medical Center confirming the feasibility and efficiency of the tool for community screening large numbers of people are published in the January issue of The Journal of Neuropsychiatry and Clinical Neurosciences.

Memory disorders researchers visited 45 community events where they asked people to take a simple, self-administered test to screen for early cognitive loss or dementia. Of the 1047 people who took the simple pen-and-paper test, 28 percent were identified with cognitive impairment, said Dr. Douglas Scharre, who developed the test with his team at Ohio State.

The SAGE test can also be taken at home by patients, who can then share the results with their physicians to help spot early symptoms of cognitive issues such as early dementia or Alzheimer’s disease, said Scharre, who is director of the Division of Cognitive Neurology and heads the Memory Disorders Research Center at Ohio State’s Wexner Medical Center. Often physicians may not recognize subtle cognitive deficits during routine office visits, he said.

“What we found was that this SAGE self-administered test correlated very well with detailed cognitive testing,” Scharre said. “If we catch this cognitive change really early then we can start potential treatments much earlier than we did without having this test.”

While the test does not diagnose problems like Alzheimer’s, it does allow doctors to get a baseline of cognitive function in their patients, so they can follow them for these problems over time.  “We can give them the test periodically and, the moment we notice any changes in their cognitive abilities, we can intervene much more rapidly,” Scharre said.

The SAGE test could also provide health care providers and caregivers an earlier indication of life-changing events that could lie ahead. Earlier research by Scharre found that four out of five people (80 percent) with mild thinking and memory (cognitive) issues will be detected by this test, and 95 percent of people without issues will have normal SAGE scores.

In this study, researchers found that SAGE’s self-administered feature, pen and paper format, and four equivalent interchangeable forms allows it to be given in almost any setting, doesn’t require any staff time to administer or to set up a computer, and makes it practical to rapidly screen large numbers of individuals in the community at the same time.

Study participants were ages 50 or older who had been recruited from a wide variety of community locations and events, including senior centers, health fairs, educational talks to lay public, independent and assisted living facilities, and free memory screens through newspaper advertisement. The study excluded individuals who indicated that they had taken SAGE previously.

Participants are tested on orientation (month + date + year); language (verbal fluency + picture naming); reasoning/computation (abstraction + calculation); visuospatial (three-dimensional construction + clock drawing); executive (problem solving) and memory abilities.

Participants were provided their score and written information about SAGE, and were advised to show it to their physician for interpretation and potential further screening or evaluation based on their health history. All were told that this test represented their baseline to be compared to future re-screening by their physician. Missing six or more points on the 22-point SAGE test usually warrants additional follow-up by the physician.

Scharre, who specializes in treating Alzheimer’s disease, said treatments for Alzheimer’s and dementia are more effective when started in the earliest stage of the disease. Unfortunately, patients with Alzheimer’s disease often wait three to four years after their symptoms first appear to seek treatment.

Some 5 million Americans have Alzheimer’s disease, and those numbers are expected to almost triple by 2050. An additional 3 percent to 22 percent of those over 60 years of age are thought to currently meet criteria for Mild Cognitive Impairment as well, Scharre said.

“Hopefully, this test will help change those situations,” Scharre said. “We are finding better treatments, and we know that patients do much better than if they start the treatments sooner than later.”

The Ohio State University Wexner Medical Center Neuroscience Program features 170 researchers and clinicians collaborating in neurology, neurosurgery, physical medicine and rehabilitation, psychiatry and neuroscience research to create better methods of prevention, detection and treatment for patients.

 

Downloads

2316258


Documents



Press Release

 

SAGE Test

 

TV Script

 

Video



News Package

 

B-Roll

 

Bites

 

News Package Nats

 

News Package With Titles

 

Audio



News Package Audio MP3

 

Bites Audio MP3

 

Images

/newmedia/mcp/osunch/2013/dec13/SAGE/8-Images/1-Photos/01_Scharre_patient.jpg
Doctors develop a pen and paper test to spot the early signs of conditions like Alzheimer's disease
Doctors at The Ohio State University Wexner Medical Center have developed a simple pen-and-paper test that patients can take themselves to spot early signs of dementia and Alzheimer's disease. It is called the SAGE test, which stands for Self-Administered Gerocognitive Examination. It was used to screen more than a thousand people over a five year study and proved to be just as effective at finding early signs of cognitive issues in patients as more in-depth, time-consuming tests. To learn more about the approach, click here: bit.ly/1bAVDxY
/newmedia/mcp/osunch/2013/dec13/SAGE/8-Images/1-Photos/02_Scharre_back.jpg
Dr. Douglas Scharre goes over test results with a patient
A simple pen-and-paper test is proving to be an effective way to spot the early signs of cognitive issues like dementia and Alzheimer`s disease. The Self-Administered Gerocognitive Examination (SAGE) test, was developed by researchers at The Ohio State University Wexner Medical Center. A new study conducted on more than a thousand patients over five years found nearly 30 percent had early signs of dementia of which they were unaware. Details on the SAGE test here: bit.ly/1bAVDxY
/newmedia/mcp/osunch/2013/dec13/SAGE/8-Images/1-Photos/03_Emily_test.jpg
A new self-administered test can spot early signs of Alzheimer`s disease
Emily Schornstein of Columbus, Ohio, takes an self-administered test designed to spot symptoms of cognitive issues like Alzheimer`s disease. Doctors at The Ohio State University Wexner Medical Center developed the Self-Administered Gerocognitive Examination (SAGE) test, as a cheap and easy way for doctors to monitor their patients` cognitive abilities as they age. To learn more about the test, click here: bit.ly/1bAVDxY
/newmedia/mcp/osunch/2013/dec13/SAGE/8-Images/1-Photos/04_Hand_test.jpg
Self-administered test helps doctors and patients track cognitive abilities
Researchers at The Ohio State University Wexner Medical Center have developed an self-administered test that can spot the early warning signs of conditions like Alzheimer`s disease. A new study shows the Self-Administered Gerocognitive Examination, (SAGE) test, is as effective in spotting changes in cognitive ability as the more expensive, in-depth testing currently used. For more on this approach click here: bit.ly/1bAVDxY
/newmedia/mcp/osunch/2013/dec13/SAGE/8-Images/1-Photos/05_SAGE_test.jpg
The SAGE test
The first self-administered test to spot early signs of conditions like Alzheimer`s disease has been developed by researchers at The Ohio State University Wexner Medical Center. The Self-Administered Gerocognitive Examination (SAGE) test, has been shown to be effective in spotting the early signs of cognitive decline, allowing patients and doctors to address conditions like Alzheimer`s disease much earlier. Details on the test here: bit.ly/1bAVDxY
/newmedia/mcp/osunch/2013/dec13/SAGE/8-Images/1-Photos/OSU-WexMedCtr-HorizK-RGBHEX.jpg
The Ohio State University Wexner Medical Center
/newmedia/mcp/osunch/2013/dec13/SAGE/8-Images/1-Photos/OSU-WexMedCtr-StackedK-RGBHEX.jpg
The Ohio State University Wexner Medical Center
7302